Antibacterial β-Glucan/Zinc Oxide Nanocomposite Films for Wound Healing

Designing polysaccharide-based antibacterial biomaterials for wound healing applications

In this study, the development and characterization of novel polymer blends based on chitosan-poly (vinyl alcohol) and physically cross-linked by freeze-thaw method for possible use in a variety of biomedical application is reported. The present investigation deals with designing savlon-loaded blend hydrogels (coined as cryogels) of poly (vinyl alcohol) (PVA) and chitosan by repeated freeze-tha...

Antibacterial Activity and Wound Healing Effect of Nitric Oxide (NO)-Releasing Chitosan Film

FOXO1, TGF-β Regulation and Wound Healing

Re-epithelialization is a complex process that involves migration and proliferation of keratinocytes, in addition to the production of cytokines and growth factors that affect other cells. The induction of transcription factors during these processes is crucial for successful wound healing. The transcription factor forkhead boxO-1 (FOXO1) has recently been found to be an important regulator of ...

Pharmacological Study of Jatropha variegata Vahl Extract as Gel for Antibacterial and Wound Healing Activities

Abstract Background: Jatropha variegata Vahl is a well-known Yemeni medicinal shrub, used traditionally in wounds treatment. Purpose: investigation of wound healing and antibacterial activities of J. variegata extract as new gel formula. Methodology: J.variegata leaves and stems were collected from Ibb Province, Yemen, and extracted by maceration in methanol. The physicochemical and biologi...

Optical and Antibacterial Studies of Zinc Magnesium Oxide Nanocomposite

Through the microwave assisted fast synthesis method, Zinc Magnesium Oxide nanocomposite was prepared. Zinc Magnesium Oxide nanocomposite heated at 500oC was used for further structural, optical and antibacterial studies. The Debye Scherrer equation was used to calculate the average particle size of the nanocomposite. The optical characterization of the oxide nanocomposite was carried out by UV...